Ejection fraction is a quantitative measurement of systolic efficiency calculated by the formula:
SV/EDV %
where SV = EDV-ESV.
The quantitative measurement of diastolic efficiency is called injection fraction.
It is calculated by the formula: (ESV-EDV)/EDV %
The other measure of diastolic efficiency is E/A ratio, which is the ratio between the filling velocity in early diastole(passive) and late diastole(due to atrial contraction - active)
The determination of diastolic efficiency is important in the diagnosis of Diastolic dysfunction or diastolic heart failure, where abnormalities in the compliance of ventricular myocardium and/or abnormalities in the valves might interfere with diastolic filling.
The initial diagnosis of diastolic dysfunction is made if the patient presents with symptoms of heart failure but ventricular function is normal.
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